Napoli want to maintain their perfect Europa League record with a difficult trip to Villarreal.
It kicks off at 18.00 GMT, follow all the action from this game, Fiorentina-Tottenham and Galatasaray-Lazio on our LIVEBLOG.
The Partenopei need to get back on track after Sunday’s 1-0 defeat at Juventus, which knocked them off the top of Serie A.
Napoli want to maintain their perfect Europa League record with a difficult trip to Villarreal.
It kicks off at 18.00 GMT, follow all the action from this game, Fiorentina-Tottenham and Galatasaray-Lazio on our LIVEBLOG.
The Partenopei need to get back on track after Sunday’s 1-0 defeat at Juventus, which knocked them off the top of Serie A.
Jorginho has pulled out of this match after coming down with flu, while Gonzalo Higuain and Lorenzo Insigne are rested in favour of Manolo Gabbiadini and Dries Mertens.
Napoli have won all six of their Europa League games this season, scoring 22 goals and conceding only three – both records in the current campaign.
Villarreal didn’t fare much worse, winning four and drawing one of their last five. The lone defeat was the opening match against group winners Rapid Vienna.
Most notably, the Spaniards emerged victorious from all three home fixtures.
Javier Jimenez is suspended for the hosts, while Eric Bailly and Samu are sidelined.
Bruno Soriano is not 100 per cent fit, but starts anyway.
There’s a familiar face on the bench, specifically ex-Milan defender Daniele Bonera.
These two clubs have faced off four times already in 2011. In the Round of 16 Villarreal emerged 2-1 winners on aggregate, but the next season Napoli won 2-0 home and away in the group stage.
Villarreal: Areola; Mario Gaspar, Musacchio, Victor Ruiz, Jaume Costa; Dos Santos, Trigueros, Bruno Soriano, Suarez; Baptistao, Soldado
Villarreal bench: Barbosa, Rukavina, Bonera, Pina, Castillejo, Bakambu, Adrian
Napoli: Reina; Hysaj, Chiriches, Koulibaly, Strinic; David Lopez, Valdifiori, Hamsik; Callejon, Gabbiadini, Mertens
Napoli bench: Gabriel, Maggio, Albiol, Allan, El Kaddouri, Higuain, Insigne
Ref: Nijhuis (NED)