Olivier Giroud and Stefano Pioli are among those saying goodbye to Milan fans against Salernitana, as Rafael Leao and Christian Pulisic also start.
It kicks off at San Siro at 19.45 UK time (18.45 GMT).
You can follow all the build-up and action as it happens from this game and Juventus-Monza on the LIVEBLOG.
The announcement finally came that Pioli would be leaving this summer, with Paulo Fonseca expected to take over, so he gets his farewell this evening.
So does Giroud, who starts upfront with Rafael Leao and Christian Pulisic, plus Simon Kjaer is on the bench.
Mike Maignan and Samuel Chukwueze are out of action.
Salernitana are already relegated in rock bottom and Toma Basic is suspended, with Federico Fazio out after emergency surgery for appendicitis.
Also absent are Kostas Manolas, Guillermo Ochoa, Jerome Boateng, Norbert Gyomber, Domagoj Bradaric, Agustin Martegani and Chukwubuikem Ikwuemesi.
Milan vs. Salernitana line-ups
Milan: Mirante; Calabria, Gabbia, Tomori, Theo Hernandez; Florenzi, Reijnders; Pulisic, Bennacer, Leao; Giroud
Salernitana: Fiorillo; Pierozzi, Pasalidis, Gyomber; Sambia, Coulibaly, Maggiore, Zanoli; Candreva, Kastanos; Tchaouna
Player statistic
| Rafael Leão |  |
22' | ||
| Olivier Giroud (Assist: Alessandro Florenzi) |
|
27' |
| 51' |  |
Niccolò Pierozzi | ||
| 64' | |
Simy (Assist: Junior Sambia) | ||
| Davide Calabria (Assist: Christian Pulisic) |
|
77' | ||
| 87' | |
Junior Sambia | ||
| 89' | |
Simy |
Match statistic
