Roma are forced into changes with Stephan El Shaarawy, Leandro Paredes and Juan Jesus for their trip to unpredictable Udinese.
It kicks off at the Dacia Arena at 14.00 GMT, follow the build-up and action from all today's Serie A games on the Liveblog.
The Giallorossi are eager to keep up with leaders Juventus and stave off pressure from Napoli.
Roma are forced into changes with Stephan El Shaarawy, Leandro Paredes and Juan Jesus for their trip to unpredictable Udinese.
It kicks off at the Dacia Arena at 14.00 GMT, follow the build-up and action from all today's Serie A games on the Liveblog.
The Giallorossi are eager to keep up with leaders Juventus and stave off pressure from Napoli.
Luciano Spalletti is forced to reshuffle, as Daniele De Rossi and Antonio Rudiger are suspended, while Mohamed Salah is on Africa Cup of Nations duty.
Diego Perotti is also on the treatment table, so El Shaarawy joins Edin Dzeko and Radja Nainggolan in attack, Juan Jesus stepping into the back three.
Udinese miss Silvan Widmer, Molla Wague and Emmanuel Agyemang Badu, so Davide Faraoni replaces the Swiss international at right-back.
Rodrigo De Paul, Duvan Zapata and Cyril Thereau complete the trident attack.
It’s safe to say Roma like this fixture, as they are unbeaten in Friuli since a 2-0 result in November 2011, managing a draw and three consecutive victories.
In fact, Udinese have lost eight of their last 11 meetings with the Giallorossi, including seven in a row.
Udinese: Karnezis; Faraoni, Danilo, Felipe, Samir; Fofana, Hallfredsson, Jankto; De Paul, Duvan Zapata, Thereau
Udinese bench: Scuffet, Perisan, Angella, Heurtaux, Adnan, Kums, Balic, L. Evangelista, Ewandro, Perica
Roma: Szczesny; Manolas, Fazio, Juan Jesus; Bruno Peres, Paredes, Strootman, Emerson; Nainggolan; El Shaarawy, Dzeko
Roma bench: Alisson, Lobont, Seck, Vermaelen, Mario Rui, Frattesi, Gerson, Totti, Tumminello