Alessio Cerci is on the bench and could well make his Milan debut at San Siro as they host giant-killers Sassuolo.
It kicks off at 14.00 GMT, click here for a match preview.
The Rossoneri ended 2014 making a charge towards the top spots, culminating in a draw away to second-placed Roma.
Sassuolo are also on impressive form and took points off the likes of Juventus, Roma, Fiorentina and Sampdoria.
Alessio Cerci is on the bench and could well make his Milan debut at San Siro as they host giant-killers Sassuolo.
It kicks off at 14.00 GMT, click here for a match preview.
The Rossoneri ended 2014 making a charge towards the top spots, culminating in a draw away to second-placed Roma.
Sassuolo are also on impressive form and took points off the likes of Juventus, Roma, Fiorentina and Sampdoria.
However, they have bad memories of San Siro, losing here 7-0 to Inter back on September 14.
Pippo Inzaghi has new signing Cerci on the bench after his international transfer came through from Atletico Madrid, where he exchanged places with Fernando Torres.
Nigel de Jong, Philippe Mexes and Pablo Armero are all suspended, while Daniele Bonera and Marco van Ginkel are injured, plus Keisuke Honda away for the Asian Cup.
This requires some serious reshuffling at the back, though at least Alex and Mattia De Sciglio are available again.
Jeremy Menez has been on the form of his life and again leads the line as a False 9 flanked by Giacomo Bonaventura and Stephan El Shaarawy.
The Little Pharaoh rediscovered his confidence over the winter break, bagging a brace in Milan’s 4-2 friendly victory over Real Madrid in Dubai.
Sassuolo miss Gianluca Pegolo, Saphir Taider and Sime Vrsaljko, but as always rely on the goals and creativity of Simone Zaza and Domenico Berardi.
It is also a special game for Francesco Acerbi, who briefly wore the Milan jersey.
MILAN: Diego Lopez; Rami, Alex, Zapata, De Sciglio; Poli, Essien, Montolivo; Bonaventura, Menez, El Shaarawy
Milan bench: Abbiati, Agazzi; Abate, Albertazzi, De Santis, Zaccardo, Muntari, Saponara, Mastour, Niang, Pazzini, Cerci
Sassuolo: Consigli; Gazzola, Cannavaro, Acerbi, Peluso; Biondini, Magnanelli, Missiroli; Berardi, Zaza, Sansone
Sassuolo bench: Pomini, Polito; Antei, Bianco, Ariaudo, Terranova, Longhi, Brighi, Chibsah, Pavoletti, Floro Flores, Floccari
Image via @acmilan