Cristiano Ronaldo, Paulo Dybala and Sami Khedira start as Juventus host Paul Pogba’s Manchester United and could qualify tonight.
It kicks off in Turin at 20.00 GMT.
You can follow the build-up and action as it happens from this game and CSKA Moscow v Roma on the LIVEBLOG.
Cristiano Ronaldo, Paulo Dybala and Sami Khedira start as Juventus host Paul Pogba’s Manchester United and could qualify tonight.
It kicks off in Turin at 20.00 GMT.
The Bianconeri have a 100 per cent record in the Champions League so far this season, winning all three games, so simply a point here tonight would be enough to ensure qualification for the Round of 16.
A victory over Manchester United would mathematically declare Juve as group winners.
Max Allegri’s men are the only unbeaten side remaining in the Champions League this season and the only side with a perfect record.
Douglas Costa, Federico Bernardeschi, Moise Kean and Emre Can miss out, while Joao Cancelo is rested in favour of Mattia De Sciglio.
Blaise Matuidi and Mario Mandzukic are also not risked from the start after minor injuries.
Khedira returns after a spell out with muscular problems, while Juan Cuadrado is chosen to complete the trident attack with Dybala and ex-Manchester United man Cristiano Ronaldo.
It was Dybala who scored the early goal for a 1-0 victory at Old Trafford, although the result didn’t reflect the extent to which Juventus out-played Manchester United.
Jose Mourinho has to do without injured Romelu Lukaku, Antonio Valencia and Diogo Dalot.
All eyes are on Pogba, as he returns to the Juventus Stadium and should be given a very warm welcome amid reports he’s considering a move back to Turin.
He runs the midfield with Nemanja Matic and Ander Herrera, while Jesse Lingard and Anthony Martial flank ex-Udinese forward Alexis Sanchez.
This means Marcus Rashford and Marouane Fellaini are ready to come off the bench and shake things up.
Juventus: Szczesny; De Sciglio, Bonucci, Chiellini, Alex Sandro; Khedira, Pjanic, Bentancur; Cuadrado, Cristiano Ronaldo, Dybala
Juventus bench: Perin, Benatia, Matuidi, Barzagli, Mandzukic, Cancelo, Rugani
Manchester United: De Gea; Young, Smalling, Lindelof, Shaw; Herrera, Matic, Pogba; Lingard, Sanchez, Martial
Manchester United bench: Sergio Romero, Bailly, Darmian, Fred, Fellaini, Mata, Rashford
Ref: Hategan (ROU)