Juventus make numerous changes, including Emre Can’s first start and Paulo Dybala back, as Cristiano Ronaldo seeks a goal against second-placed Sassuolo.
It kicks off at 14.00 UK time (13.00 GMT).
Follow the build-up and action as it happens from all today’s Serie A games on the LIVEBLOG.
This is an unexpected top of the table showdown between the only two sides remaining who are unbeaten this season.
Juventus make numerous changes, including Emre Can’s first start and Paulo Dybala back, as Cristiano Ronaldo seeks a goal against second-placed Sassuolo.
It kicks off at 14.00 UK time (13.00 GMT).
Follow the build-up and action as it happens from all today’s Serie A games on the LIVEBLOG.
This is an unexpected top of the table showdown between the only two sides remaining who are unbeaten this season.
Max Allegri has his eye on the upcoming Champions League meeting with Valencia, so Miralem Pjanic, Giorgio Chiellini and Joao Cancelo are rested.
Emre Can gets his first start since leaving Liverpool as a free agent, while Medhi Benatia and Mattia De Sciglio also step in.
Cristiano Ronaldo is still looking for his first goal in a Bianconeri jersey and is supported by Dybala and Mario Mandzukic, so La Joya returns to the starting XI after two games on the bench.
Federico Bernardeschi makes way, while Leonardo Spinazzola and Andrea Barzagli are out injured.
Sassuolo are the surprise outfit of the season so far and, along with Juve, the only side still unbeaten in the division.
Coach Roberto De Zerbi already did an impressive job last term with Benevento, although he was unable to rescue them following a disastrous start before he took over.
The Neroverdi have strengthened with Kevin-Prince Boateng, joining Domenico Berardi in the trident attack, with Filip Djuricic rather than Federico Di Francesco.
Francesco Magnanelli is not 100 per cent fit, so ex-Milan starlet Manuel Locatelli takes the midfield reins.
They have already beaten Inter and Genoa, snatching the latest of last-gasp draws with Cagliari, and are the top scorers in the league so far.
Curiously, defenders Pol Lirola, Rogerio and Giangiacomo Magnani are all either on loan from Juventus or the Bianconeri have a buy-back clause on them.
Sassuolo have a dire record in Turin, losing all five of their previous Serie A visits.
Juventus: Szczesny; De Sciglio, Bonucci, Benatia, Alex Sandro; Emre Can, Khedira, Matuidi; Dybala, Mandzukic, Cristiano Ronaldo
Sassuolo: Consigli; Lirola, Marlon, Ferrari, Rogerio; Duncan, Locatelli, Bourabia; Berardi, Boateng, Djuricic