Join us for all the build-up and action as it happens from the Derby di Campania between Salernitana and leaders Napoli, plus Fiorentina hosting Torino in a mid-table tussle.
We begin at 17.00 GMT at the Stadio Arechi, where plenty of star names will be on show as the local rivals face off.
It is a rebirth for Salernitana, who sacked coach Davide Nicola only to recall him 48 hours later, while Napoli may be nine points clear at the top of the Serie A table, but suffered a shock Coppa Italia elimination to 10-man Cremonese midweek.
At 19.45 GMT, Fiorentina and Torino go head-to-head for position, as they have an identical record going into this weekend and both bumped up the standings thanks to the 15-point Juventus penalty.