Milan make more changes for the trip to Claudio Ranieri’s Cagliari, including Yacine Adli in midfield, Christian Pulisic, Noah Okafor and Samuel Chukwueze upfront.
It kicks off at the Unipol Domus at 17.30 UK time (16.30 GMT).
The Rossoneri got back on track with a slender victory over Verona, but it was another far from impressive performance, plus they lost Rade Krunic to injury for several weeks.
He joins Mike Maignan, Luka Jovic, Pierre Kalulu, Ismael Bennacer and Mattia Caldara on the treatment table, but Theo Hernandez returns to the side.
It means Yacine Adli goes from barely getting any playing time to being thrown into the starting XI, while there is an all-new strike force too, resting Rafael Leao and Olivier Giroud.
The 3-4-3 formation is also scrapped for a return to 4-3-3.
Cagliari are still without a win this season, drawing only 0-0 with Torino and Udinese.
They remain decimated by injuries which rule out Leonardo Pavoletti, Jakub Jankto, Gianluca Lapadula, Marko Rog, Gaston Pereiro, Marco Mancosu and Elio Capradossi.
There is some good news, as Leonardo Pavoletti and Alessandro Di Pardo return, while Mateusz Wieteska has completed his ban.
Andrea Petagna came through the Milan youth academy and he gets his first start for the Sardinians, who move to a four-man defence.
Cagliari: Radunovic; Zappa, Wieteska, Dossena, Hatzidiakos; Nandez, Makoumbou, Sulemana, Augello; Petagna, Luvumbo
Milan: Sportiello; Florenzi, Thiaw, Tomori, Theo Hernandez; Loftus-Cheek, Adli, Reijnders; Chukwueze, Okafor, Pulisic
Player statistic
| Zito Luvumbo (Assist: Nahitan Nández) |
 |
29' | ||
| 40' | |
Noah Okafor | ||
| Mateusz Wieteska |  |
42' | ||
| 45+1' | |
Fikayo Tomori |
| 48' | |
Ruben Loftus-Cheek | ||
| Gabriele Zappa | |
53' | ||
| 60' | |
Ruben Loftus-Cheek (Assist: Christian Pulisic) | ||
| Gaetano Oristanio | |
79' |
Match statistic
