Roma must choose between Mohamed Salah and Diego Perotti in a 3-4-2-1 formation against Lyon in the Europa League tonight.
The first leg of the Round of 16 tie kicks off in France at 20.05 GMT.
Antonio Rudiger is suspended for this game, while Alessandro Florenzi is on the treatment table and January signing Clement Grenier cup-tied.
According to the latest reports, Luciano Spalletti will stick with three at the back after a move to four proved to be a mistake in the 2-1 home defeat to Napoli last week.
Roma must choose between Mohamed Salah and Diego Perotti in a 3-4-2-1 formation against Lyon in the Europa League tonight.
The first leg of the Round of 16 tie kicks off in France at 20.05 GMT.
Antonio Rudiger is suspended for this game, while Alessandro Florenzi is on the treatment table and January signing Clement Grenier cup-tied.
According to the latest reports, Luciano Spalletti will stick with three at the back after a move to four proved to be a mistake in the 2-1 home defeat to Napoli last week.
As always in the Europa League, Alisson is given the nod in between the sticks, with Juan Jesus stepping into the defence.
The choice is expected to be between Salah and Perotti supporting Radja Nainggolan and Edin Dzeko.
Olympique Lyonnais dropped down from the Champions League, where they finished third in their group behind Juventus and Sevilla.
Alexandre Lacazette leads the way with Nabil Fekir and either Mathieu Valbuena or Maxwel Cornet.
Memphis Depay is cup-tied following his January transfer from Manchester United.
There is some uncertainty in defence, but impressive 20-year-old Mouctar Diakhaby should get the spot ahead of ex-Roma man Mapou Yanga-Mbiwa.
The referee this evening will be England’s Anthony Taylor.
Probable line-ups
Olympique Lyonnais: Lopes; Rafael, Mammana, Diakhaby, Morel; Gonalons, Tousart, Tolisso; Fekir, Lacazette, Valbuena
Lyon bench: Gorgelin, Yanga-Mbiwa, Jallet, Darder, Ferri, Ghezzal, Cornet
On a yellow card: Rafael, Darder, Gonalons, Cornet
Suspended: None
Unavailable: Depay (cup-tied)
Roma: Alisson; Manolas, Fazio, Juan Jesus; Bruno Peres, De Rossi, Strootman, Emerson Palmieri; Salah, Nainggolan; Dzeko
Roma bench: Szczesny, Vermaelen, Mario Rui, Paredes, Perotti, El Shaarawy, Totti
On a yellow card: Paredes
Suspended: Rudiger
Unavailable: Grenet (cup-tied), Florenzi