Roma have limited options to choose from, while Milan hope Krzysztof Piatek and Lucas Paquetà can continue their remarkable starts.
It kicks off at 19.30 GMT, click here for a match preview.
There is only one point separating these teams going into the showdown for fourth place and with it a Champions League spot.
Roma have limited options to choose from, while Milan hope Krzysztof Piatek and Lucas Paquetà can continue their remarkable starts.
It kicks off at 19.30 GMT, click here for a match preview.
There is only one point separating these teams going into the showdown for fourth place and with it a Champions League spot.
Eusebio Di Francesco is hanging by a thread after fumbling a 3-0 lead to draw 3-3 with Atalanta in Serie A, then crashing out of the Coppa Italia due to an historic 7-1 drubbing by Fiorentina.
He has few genuine choices to make here, because Bryan Cristante and Steven Nzonzi are both suspended, with Diego Perotti, Juan Jesus and Cengiz Under injured.
This means Daniele De Rossi has to start in midfield with Lorenzo Pellegrini, the veteran’s first start in three months following a knee injury.
Alessandro Florenzi is expected to move up to maintain the 4-2-3-1 formation with Nicolò Zaniolo and Stephan El Shaarawy behind Edin Dzeko, as the Bosnian’s two-match ban applies to the Coppa Italia and not Serie A.
The only alternative is to use Justin Kluivert there, but considering how enraged Di Francesco was with the Dutchman after his sluggish substitute appearance against Atalanta, it’s unlikely.
Davide Santon is the favourite to start at right-back rather than Rick Karsdorp.
Milan are fresh from a 2-0 Coppa Italia quarter-final win over Napoli, in which Piatek made the ideal full debut by bagging both goals in the opening 27 minutes.
It’s safe to say the former Genoa striker will get his first Serie A start in a Rossoneri jersey, leaving Patrick Cutrone on the bench, flanked by Suso and Hakan Calhanoglu.
Cristian Zapata, Pepe Reina, Mattia Caldara, Lucas Biglia and Jack Bonaventura are still out of action, so Mateo Musacchio joins ex-Roma youth product Alessio Romagnoli in defence.
Paquetà has started every match since his arrival from Flamengo and there’s no sign of the Brazilian resting any time soon.
Probable line-ups
Roma: Olsen; Karsdorp, Manolas, Fazio, Kolarov; De Rossi, Lorenzo Pellegrini; Florenzi, Zaniolo, El Shaarawy; Dzeko
Milan: G Donnarumma; Calabria, Musacchio, Romagnoli, Rodriguez; Kessie, Bakayoko, Paquetá; Suso, Piatek, Calhanoglu