Roma and Juventus go head-to-head in the Scudetto showdown, as Francesco Totti aims to re-open the title race.
It kicks off at 20.00 GMT, click here to join in our LIVEBLOG.
There are nine points separating first and second, while Torino did Roma a huge favour last night by beating third-placed Napoli, ensuring whatever happens this weekend they will retain their spot.
Roma and Juventus go head-to-head in the Scudetto showdown, as Francesco Totti aims to re-open the title race.
It kicks off at 20.00 GMT, click here to join in our LIVEBLOG.
There are nine points separating first and second, while Torino did Roma a huge favour last night by beating third-placed Napoli, ensuring whatever happens this weekend they will retain their spot.
The last time these sides met it was a fiery 3-2 Juve victory in Turin, although Rudi Garcia had complaints about the refereeing on all three goals.
Roma slipped back after a series of stalemates and have drawn their last four home fixtures, but were given a huge confidence boost by Thursday’s 2-1 Europa League victory over Feyenoord.
Totti starts in the trident attack with Adem Ljajic and Gervinho, who both found the net in Rotterdam.
Seydou Doumbia, Victor Ibarbo, Douglas Maicon, Kevin Strootman and Leandro Castan are sidelined with Juan Manuel Iturbe able to play only up to an hour.
Surprisingly, Radja Nainggolan is benched in favour of Miralem Pjanic and Seydou Keita.
Juventus have injury problems too, as Andrea Pirlo is out for three weeks, while Paul Pogba and Arturo Vidal both had issues over the last few days.
Pogba has been rested due to that inflammation of the thigh muscle, but Vidal does start despite a bruised back.
Stefano Sturaro was a late addition to the injury list along with Kwadwo Asamoah, Romulo and Luca Marrone.
With the midfielders dropping out in numbers, Max Allegri returns to a 3-5-2 system with Stephan Lichtsteiner and Patrice Evra as wing-backs, moving Roberto Pereyra into the middle.
Capocannoniere Carlos Tevez is partnered by impressive Alvaro Morata, preferred to Fernando Llorente.
In Serie A, Roma’s last victory over Juventus was 1-0 here in February 2013, followed by three consecutive defeats home and away.
In fact, the Giallorossi have lost five of their last six Serie A encounters with Juve.
Last season the Bianconeri emerged 1-0 winners from the Olimpico thanks to Daniel Osvaldo’s goal deep into stoppages.
Roma: De Sanctis; Torosidis, Manolas, Yanga-Mbiwa, Holebas; Pjanic, De Rossi, Keita; Gervinho, Totti, Ljajic
Roma bench: Skorupski, Curci, Astori, Spolli, Cole, Nainggolan, Florenzi, Ucan, Paredes, Verde, Sanabria, Iturbe
Juventus: Buffon; Caceres, Bonucci, Chiellini; Lichtsteiner, Vidal, Marchisio, Pereyra, Evra; Morata, Tevez
Juventus bench: Storari, Rubinho, Barzagli, Ogbonna, De Ceglie, Padoin, Pogba, Pepe, Coman, Llorente, Matri