Roma give Mattia Destro a chance as they visit Paulo Dybala’s exciting giant-killers Palermo.

It kicks off at the Stadio Renzo Barbera at 19.45 GMT, click here for the match preview.

Francesco Totti’s spectacular brace clawed back a 2-2 draw in the Rome Derby last week, but still saw the gap at the top of the table expanded to three points.

On the other hand, Palermo had racked up 11 points from five rounds during a club record nine-game unbeaten Serie A run.

Roma give Mattia Destro a chance as they visit Paulo Dybala’s exciting giant-killers Palermo.

It kicks off at the Stadio Renzo Barbera at 19.45 GMT, click here for the match preview.

Francesco Totti’s spectacular brace clawed back a 2-2 draw in the Rome Derby last week, but still saw the gap at the top of the table expanded to three points.

On the other hand, Palermo had racked up 11 points from five rounds during a club record nine-game unbeaten Serie A run.

That was terminated in some style by Sunday’s 4-3 defeat at Fiorentina, which notably saw Dybala miss out due to an injury in the warm-up.

The 21-year-old Argentine who the club have rated at €40m is back in the starting XI and raring to go alongside Franco Vazquez, who signed a contract extension this week.

The Rosanero have lost at home only once this season along with five victories and three draws.

This fixture hasn’t been played since an epic 3-3 draw in 2009-10, so there’s a history of fireworks here.

Daniele De Rossi and Radja Nainggolan sit out bans, while Gervinho and Seydou Keita are away on Africa Cup of Nations duty.

Mattia Destro is given a rare start amid swirling transfer rumours linking him with the likes of Milan, Torino and Tottenham.

Alessandro Florenzi is re-routed to the right-back role in place of Douglas Maicon, while Carlos Paredes also gets the nod in midfield alongside Kevin Strootman.

Palermo: Sorrentino; Vitiello, Gonzalez, Andelkovic; Morganella, Rigoni, Maresca, Barreto, Lazaar; Vazquez, Dybala

Palermo bench: Ujkani, Munoz, Joao Silva, Emerson, Della Rocca, Bolzoni, Chochev, Terzi, Quaison, Feddal, Daprelà, Belotti

Roma: De Sanctis; Florenzi, Astori, Yanga-Mbiwa, Holebas; Paredes, Strootman, Pjanic; Iturbe, Destro, Ljajic

Roma bench: Skorupski, Cole, Borriello, Totti, Maicon, Manolas, Ucan, Somma, Pellegrini, Verde, Emanuelson, Calabresi

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