Miralem Pjanic, Paulo Dybala and Christian Eriksen are dropped for the Derby d’Italia, as Juventus and Inter pull a few surprises for this Scudetto showdown.
It kicks off behind closed doors at 19.45 GMT.
You can follow the build-up and action as it happens on the LIVEBLOG.
This game was meant to be played a week ago, but called off amid rows over who should be allowed into the stands, if anyone, during the Coronavirus outbreak.
Miralem Pjanic, Paulo Dybala and Christian Eriksen are dropped for the Derby d’Italia, as Juventus and Inter pull a few surprises for this Scudetto showdown.
It kicks off behind closed doors at 19.45 GMT.
You can follow the build-up and action as it happens on the LIVEBLOG.
This game was meant to be played a week ago, but called off amid rows over who should be allowed into the stands, if anyone, during the Coronavirus outbreak.
Today’s figures show precisely why all the matches are behind closed doors, because there have now been 7,375 positive tests in Italy and 366 deaths, an increase of 133 over the last 24 hours.
The Lega Serie A, Minister for Sport and Players’ Association continue to argue over whether the league should be suspended entirely and it’s likely that will be the case from Tuesday.
Meanwhile, this is a top of the table showdown, as Juventus need to catch up to Lazio, while Inter risk falling further behind.
Maurizio Sarri rings the changes after some dismal recent performances, as he drops the previously untouchable Pjanic, who has been struggling to provide the kind of tempo that the coach wants in midfield.
Instead, Rodrigo Bentancur takes over with Aaron Ramsey and Blaise Matuidi, while Gonzalo Higuain and Douglas Costa join Cristiano Ronaldo in attack, sending Juan Cuadrado to right-back.
Giorgio Chiellini is fit again, but only on the bench, as Matthijs de Ligt retains his spot alongside Leonardo Bonucci.
Inter also drop a big name, as Antonio Conte doesn’t feel January signing Eriksen is yet ready to run the midfield, so Marcelo Brozovic and Matias Vecino remain in charge.
Alessandro Bastoni is preferred to Diego Godin in the back three, but the big news is the return of Samir Handanovic in goal.
The captain had been out of action since February 1 with a hairline fracture in the little finger of his left hand.
This is Antonio Conte’s first time back at the Juventus Stadium as an opponent, but there are no fans to give him a fiery welcome.
Juventus: Szczesny; Cuadrado, De Ligt, Bonucci, Alex Sandro; Ramsey, Bentancur, Matuidi; Douglas Costa, Higuain, Cristiano Ronaldo
Juventus bench: Pinsoglio, Buffon, De Sciglio, Chiellini, Pjanic, Khedira, Dybala, Danilo, Rugani, Rabiot, Bernardeschi
Inter: Handanovic; Skriniar, De Vrij, Bastoni; Candreva, Vecino, Brozovic, Barella, Young; R Lukaku, Lautaro Martinez
Inter bench: Padelli, Berni, Godin, Gagliardini, Alexis Sanchez, Ranocchia, Asamoah, Borja Valero, Eriksen, Esposito, D’Ambrosio, Biraghi
Ref: Guida