Juventus have the chance to go 11 points clear tonight, but have to reshuffle against unpredictable Sassuolo.
It kicks off at 20.00 GMT, click here to follow our LIVEBLOG.
As Roma were held 0-0 by Chievo on Sunday, a win would put Juve 11 points clear at the top of the table.
However, Gigi Buffon, Martin Caceres and Andrea Pirlo are unavailable, the goalkeeper coming down with flu symptoms this afternoon.
Juventus have the chance to go 11 points clear tonight, but have to reshuffle against unpredictable Sassuolo.
It kicks off at 20.00 GMT, click here to follow our LIVEBLOG.
As Roma were held 0-0 by Chievo on Sunday, a win would put Juve 11 points clear at the top of the table.
However, Gigi Buffon, Martin Caceres and Andrea Pirlo are unavailable, the goalkeeper coming down with flu symptoms this afternoon.
Fiorentina came away with a 2-1 Coppa Italia semi-final win here on Thursday evening, becoming the first side to conquer the Juventus Stadium since Bayern Munich in April 2013.
Sassuolo are capable of causing upsets and already held Juve to a draw earlier this season, with strikers Simone Zaza and Domenico Berardi in an all-attack 4-3-3 system.
Sassuolo have Alessandro Gazzola suspended, while Luca Antei, Paolo Cannavaro, Gianluca Pegolo and Emanuele Terranova are on the treatment table.
Juventus: Storari, Lichtsteiner, Bonucci, Chiellini, Evra, Vidal, Marchisio, Pogba, Pereyra, Tevez, Morata
Juventus bench: Rubinho, Audero, Barzagli, Ogbonna, De Ceglie, Padoin, Sturaro, Pepe, Llorente, Matri
Sassuolo: Consigli; Vrsaljko, Acerbi, Peluso, Longhi; Brighi, Magnanelli, Missiroli; Berardi, Zaza, Sansone
Sassuolo bench: Pomini, Polito; Bianco, Natali, Fontanesi, Biondini, Chibsah, Taider, Donis, Floro Flores, Lazarevic, Floccari