Lukas Podolski is on the Inter bench, as Hernanes, Mateo Kovacic and Mauro Icardi face Juventus in the Derby d’Italia.
It kicks off at 20.00 GMT, click here for a match preview.
Juve need at least a point to stay clear of Roma following a controversial 1-0 victory away to Udinese earlier today.
They also require a confidence booster, having ended 2014 with an Italian Super Cup defeat to Napoli on penalties in Doha.
Lukas Podolski is on the Inter bench, as Hernanes, Mateo Kovacic and Mauro Icardi face Juventus in the Derby d’Italia.
It kicks off at 20.00 GMT, click here for a match preview.
Juve need at least a point to stay clear of Roma following a controversial 1-0 victory away to Udinese earlier today.
They also require a confidence booster, having ended 2014 with an Italian Super Cup defeat to Napoli on penalties in Doha.
Martin Caceres is back from a long-term injury to sit on the bench, but Andrea Barzagli, Kwadwo Asamoah and Romulo remain sidelined.
Fernando Llorente is picked alongside Capocannoniere Carlos Tevez, while Andrea Pirlo, Arturo Vidal and Paul Pogba share the midfield.
Inter finally completed Podolski’s transfer from Arsenal on Monday afternoon, but he is only on the bench despite Rodrigo Palacio coming down with flu symptoms this morning.
Mauro Icardi has a history of scoring goals against Juventus, so will be one to watch along with Croatia international Mateo Kovacic and Hernanes in supporting roles.
Yuto Nagatomo is away on Asian Cup duties with Japan.
Juventus: Buffon; Lichtsteiner, Bonucci, Chiellini, Evra; Marchisio, Pirlo, Pogba; Vidal; Tevez, Llorente
Juventus bench: Storari, Rubinho, Caceres, Ogbonna, Pepe, Morata, Coman, Giovinco, Padoin, Pereyra, Mattiello, Marrone
Inter: Handanovic; Campagnaro, Ranocchia, Juan Jesus, D'Ambrosio; Guarin, Medel, Kuzmanovic; Kovacic, Hernanes; Icardi
Inter bench: Carrizo, Andreolli, Osvaldo, Podolski, Vidic, Obi, Dodò, Puscas, Krhin, Donkor, M'Vila, Bonazzoli
Image via @inter