Italy look to Alessandro Florenzi, Graziano Pellè and Eder against Alvaro Morata’s unchanged Spain in the Euro 2016 Round of 16.
It kicks off in Paris at 17.00 UK time (16.00 GMT).
Follow all the build-up and action while giving your views on our LIVEBLOG.
The Azzurri are out for revenge after losing the Euro 2012 Final 4-0 and haven’t beaten Spain in a competitive match since the 1994 World Cup quarter-final.
Italy look to Alessandro Florenzi, Graziano Pellè and Eder against Alvaro Morata’s unchanged Spain in the Euro 2016 Round of 16.
It kicks off in Paris at 17.00 UK time (16.00 GMT).
Follow all the build-up and action while giving your views on our LIVEBLOG.
The Azzurri are out for revenge after losing the Euro 2012 Final 4-0 and haven’t beaten Spain in a competitive match since the 1994 World Cup quarter-final.
However, they drew after 90 minutes at Euro 2008, the group stage of Euro 2012 and the 2013 Confederations Cup.
Antonio Conte’s favoured 3-5-2 formation has traditionally caused problems for Spain and he sticks to it here, although Emanuele Giaccherini could push up in possession to form a 3-4-3 system.
Antonio Candreva is ruled out by a thigh injury, so Roma’s Alessandro Florenzi replaces him on the right.
Mattia De Sciglio won the battle with Matteo Darmian and Stephan El Shaarawy to start on the left flank.
The BBC defensive unit – Leonardo Bonucci, Andrea Barzagli and Giorgio Chiellini – with Gigi Buffon face their former Juventus teammate Morata.
Spain field an unchanged line-up for the fourth game running in Euro 2016, as Nolito and David Silva try to make the most of Andres Iniesta’s creativity.
There could be a slight adjustment from 4-3-3 to 4-1-4-1 with Sergio Busquets protecting the defence.
La Furia Roja won their opening two matches against the Czech Republic and Turkey, but were surprisingly beaten 2-1 by Croatia.
That bumped them down to second in their group, which is why they are facing Italy so early in the tournament.
The winners of this tie will go on to face Germany in the quarter-finals.
It’s worth noting that Italy have numerous players one yellow card away from suspension, specifically Barzagli, Bonucci, Buffon, Chiellini, Daniele De Rossi, Eder, Lorenzo Insigne, Thiago Motta, Salvatore Sirigu and Simone Zaza.
The only Spain player who will be banned with another booking is Sergio Ramos.
Italy: Buffon; Barzagli, Bonucci, Chiellini; Florenzi, Parolo, De Rossi, Giaccherini, De Sciglio; Pellè, Eder
Spain: De Gea; Juanfran, Piqué, Ramos, Alba; Busquets; Silva, Fabregas, Iniesta, Nolito; Morata
Ref: Cakir (TUR)