It’s a massive Derby d’Italia, as Inter rely on Ever Banega, Mauro Icardi and Antonio Candreva against Juventus’ Mario Mandzukic, Paulo Dybala and Miralem Pjanic.
It kicks off at 17.00 UK time (16.00 GMT), follow the build-up and action on our LIVEBLOG.
It’s a massive Derby d’Italia, as Inter rely on Ever Banega, Mauro Icardi and Antonio Candreva against Juventus’ Mario Mandzukic, Paulo Dybala and Miralem Pjanic.
It kicks off at 17.00 UK time (16.00 GMT), follow the build-up and action on our LIVEBLOG.
The Nerazzurri are already under huge pressure amid reports Frank de Boer could be sacked, with Rudi Garcia, Cesare Prandelli and Fabio Capello the potential successors at San Siro.
A shock 2-0 home defeat to Hapoel Beer-Sheva in the Europa League on Thursday made the situation critical, managing just one win in four competitive games and three goals – all of them scored by Icardi.
Juventus also had a disappointing midweek foray into continental competition, held to a goalless draw by Sevilla in the Champions League.
Both sides have a point to prove on top of the usual bitter rivalry that goes along with this fixture, whose history got even more intense after the 2006 Calciopoli scandal.
Ivan Perisic, Cristian Ansaldi and Marco Andreolli are out injured and Gabigol only arrived yesterday from Brazil, so isn’t even on the bench.
Marcelo Brozovic was dropped, reportedly for disciplinary reasons, though he took to Instagram last night to insist he was “excluded for no reason.”
Joao Mario returns, as he is ineligible for the Europa League, with Antonio Candreva, Ever Banega and Eder supporting Icardi.
Today Argentina Coach Edgardo Bauzer complained that Inter were using Banega too deep, so this more advanced role should provide a little more creative spark.
Juventus are still missing Claudio Marchisio and Stefano Sturaro.
Gonzalo Higuain is somewhat surprisingly rested in favour of Mario Mandzukic, while Medhi Benatia steps in for Andrea Barzagli.
Dybala leads the attack with support in midfield from ex-Roma star Pjanic, who many wanted to see start against Sevilla.
Inter: Handanovic; D’Ambrosio, Miranda, Murillo, Santon; Joao Mario, Medel; Candreva, Banega, Eder; Icardi
Inter bench: Carrizo, Melo, Kondogbia, Palacio, Jovetic, Biabiany, Ranocchia, Gnoukouri, Perisic, Nagatomo, Yao, Miangue
Juventus: Buffon; Benatia, Bonucci, Chiellini; Lichtsteiner, Khedira, Pjanic, Asamoah, Alex Sandro; Dybala, Mandzukic
Juventus bench: Neto, Audero, Barzagli, Rugani, Dani Alves, Evra, Hernanes, Lemina, Cuadrado, Pjaca, Higuain