Roma look to Kevin Strootman and Diego Perotti for their tricky trip to Genoa, as second place is within reach.
It kicks off at 18.00 UK time (17.00 GMT), follow the build-up and action on our LIVEBLOG.
Luciano Spalletti’s men are now mathematically sure of a top three finish, but second is precious because it means entry into the Champions League group phase without the need for a preliminary round.
Roma look to Kevin Strootman and Diego Perotti for their tricky trip to Genoa, as second place is within reach.
It kicks off at 18.00 UK time (17.00 GMT), follow the build-up and action on our LIVEBLOG.
Luciano Spalletti’s men are now mathematically sure of a top three finish, but second is precious because it means entry into the Champions League group phase without the need for a preliminary round.
They beat Napoli with a late Radja Nainggolan strike last week, but go into Marassi without suspended Miralem Pjanic.
Alessandro Florenzi, Vasilis Torosidis and Iago Falque are injured, while Seydou Keita is not 100 per cent fit, so Douglas Maicon and Daniele De Rossi get rare starts, while Perotti faces the club he left in January.
Above all, Strootman is in the starting XI for the first time in 463 days, since a 1-1 with Fiorentina on January 25, 2015.
The Dutch midfielder was one of the best players in Europe before suffering a series of knee ligament problems starting in March 2014, requiring three operations.
Again, there’s no room for Edin Dzeko in the starting XI.
Genoa have a solid home record and want to keep the enthusiasm up ahead of this weekend’s Derby della Lanterna against local rivals Sampdoria.
Alessio Cerci and Mattia Perin miss out for the hosts, but Nicolas Burdisso (ex-Roma) and Goran Pandev return.
This fixture tends to be entertaining, as it hasn’t ended in a draw since September 1992. That 0-0 result was followed by eight home wins and three for the visitors.
In fact, these sides haven’t shared the spoils home or away since January 1994.
Roma have won seven of their last eight meetings with Genoa, home and away, faltering only in May 2014.
Genoa: Lamanna; Munoz, Burdisso, Izzo; Fiamozzi, Rincon, Dzemaili, Tachtsidis, Laxalt; Pavoletti, Suso
Roma: Szczesny; Maicon, Manolas, Rudiger, Digne; Nainggolan, De Rossi, Strootman; Salah, Perotti, El Shaarawy
Ref: Gervasoni