Both teams are desperate for points, as Fiorentina must escape the drop with Dusan Vlahovic and Franck Ribery, while Federico Chiesa is injured for struggling Juventus.
It kicks off at the Stadio Franchi at 14.00 UK time (13.00 GMT).
Both teams are desperate for points, as Fiorentina must escape the drop with Dusan Vlahovic and Franck Ribery, while Federico Chiesa is injured for struggling Juventus.
It kicks off at the Stadio Franchi at 14.00 UK time (13.00 GMT).
There is a long-running rivalry between these clubs that goes back decades and it only became even more bitter after Chiesa pushed for a transfer to the Bianconeri last summer.
He won’t return to face his former teammates, as he is out injured along with Merih Demiral, but Paulo Dybala gets the nod rather than Alvaro Morata alongside Cristiano Ronaldo.
Juan Cuadrado is another former Fiorentina man, while the Viola start ex-Juve defender Martin Caceres.
It has been a dismal season for the Tuscans, who fired Beppe Iachini and had to bring him back suddenly when Cesare Prandelli quit.
They received a boost with the midweek 2-1 win away to Verona, but Giacomo Bonaventura was booked and is therefore suspended, with Borja Valero and Aleksandar Kokorin injured.
Vlahovic and Ribery again lead the way, with Gaetano Castrovilli stepping in for Bonaventura.
Fiorentina beat Juventus 3-0 in Turin back in December, but that game was under Prandelli and affected by an early Cuadrado red card.
Fiorentina: Dragowski; Caceres, Milenkovic, Pezzella, Igor; Venuti, Amrabat, Pulgar, Castrovilli; Vlahovic, Ribery
Juventus: Szczesny; De Ligt, Bonucci, Chiellini; Cuadrado, Bentancur, Rabiot, Alex Sandro; Ramsey; Dybala, Ronaldo
Ref: Massa