Napoli target a third consecutive victory and a repeat of last year’s 7-1 success as they visit Bologna’s Stadio Dall’Ara.
It kicks off at 19.45 UK time (18.45 GMT), follow the build-up and action on the LIVEBLOG.
The Partenopei are on fine form, winning all four competitive matches so far this season between Serie A and the Champions League preliminary round.
Napoli target a third consecutive victory and a repeat of last year’s 7-1 success as they visit Bologna’s Stadio Dall’Ara.
It kicks off at 19.45 UK time (18.45 GMT), follow the build-up and action on the LIVEBLOG.
The Partenopei are on fine form, winning all four competitive matches so far this season between Serie A and the Champions League preliminary round.
There’s a difficult European trip to Ukraine and Shakhtar Donetsk on Wednesday, but Maurizio Sarri keeps squad rotation to a minimum.
Dries Mertens leads the way flanked by Jose Callejon and Lorenzo Insigne.
There were concerns Marek Hamsik would be rested after coming back tired from international duty with Slovakia, but he still starts with Jorginho and Allan, despite rumours Piotr Zielinski and Amadou Diawara would play.
The only real change is at the back, where Vlad Chiriches steps in for Raul Albiol.
Bologna still have nightmares about last year’s edition of this fixture, as the 7-1 defeat was their heaviest ever on home turf in the top flight.
Roberto Donadoni, who celebrated his birthday yesterday, has to do without Vasilis Torosidis, Cheick Keita, Angelo Da Costa and Cesar Falletti.
Mattia Destro is supported in the trident by Federico Di Francesco, Simone Verdi and debutant Rodrigo Palacio.
The former Genoa and Inter veteran arrived as a free agent and is pushed straight into the starting XI.
Bologna have the opportunity to go unbeaten for the opening three rounds for the first time since 2002-03.
On the other hand, Napoli can match their all-time record of eight consecutive Serie A victories, set from December 2015 to February 2016.
Bologna: Mirante; Krafth, Helander, Maietta, Masina; Poli, Pulgar; Verdi, Palacio, Di Francesco; Destro
Napoli: Reina; Hysaj, Chiriches, Koulibaly, Ghoulam; Allan, Jorginho, Hamsik; Callejon, Mertens, Insigne