Roma bring back Tammy Abraham and Lorenzo Pellegrini with Paulo Dybala in the Europa League quarter-final with Santiago Gimenez’s Feyenoord.
It kicks off at the De Kuip stadium in Rotterdam at 17.45 UK time (16.45 GMT).
These sides met in last season’s Conference League Final in Tirana, won 1-0 by the Giallorossi thanks to a Nicolò Zaniolo strike.
Due to fears over crowd trouble, there will be no away fans in this game or for the second leg at the Stadio Olimpico next Thursday.
Jose Mourinho brings Abraham and Pellegrini back into the starting XI after the 1-0 win over Torino, with Dybala completing the attack, Rick Karsdorp and Ola Solbakken injured.
Feyenoord miss Quinten Timber, but rely on strikers Santiago Gimenez and Alireza Jahanbakhsh, the latter recovering after a problem in the warm-up on Sunday.
Goalkeeper Justin Bijlow is also back in the squad for the first time since an injury to his wrist in early February.
They are at the top of the Eredivisie and have not been in the Europa League quarter-finals since 2002.
Lazio were already eliminated by Feyenoord in the group phase.
Feyenoord: Bijlow; Geertruida, Trauner, Hancko, Hartman; Kokcu, Szymanski, Wieffer; Jahanbakhsh, Gimenez, Idrissi.
Roma: Rui Patricio; Mancini, Smalling, Ibanez; Zalewski, Cristante, Matic, Spinazzola; Pellegrini, Dybala; Abraham
Ref: Sanchez (ESP)
Player statistic
Mats Wieffer | 18' | |||
Sebastian Szymanski | 35' | |||
43' | Lorenzo Pellegrini |
Mats Wieffer (Assist: Oussama Idrissi) |
54' |