The celebrations are already getting underway before the Serie A trophy is presented to the Napoli squad at the Stadio Diego Armando Maradona.
Their final game of the season against Sampdoria kicks off at 17.30 UK time (16.30 GMT).
Although the Scudetto was clinched with five rounds to spare, the fans are still partying in the streets on their way to the arena.
There will also be giant screens set up around the city so that those who couldn’t get tickets to the game can still participate in the event.
It will include singers such as Nino D’Angelo, Arisa, Emma and Gigi D’Alessio.