Juventus form a new strike partnership of Dusan Vlahovic and Arkadiusz Milik for the trip to Sassuolo, where Armand Laurienté and Davide Frattesi are the key names.
It kicks off at the Mapei Stadium in Reggio Emilia at 17.00 UK time (16.00 GMT).
You can follow all the build-up and action as it happens from today’s Serie A games on the LIVEBLOG.
The Bianconeri have had a mixed week, losing in Serie A to Lazio and then taking a slender 1-0 lead over Sporting CP in the Europa League quarter-final.
Alex Sandro is suspended, with Moise Kean joining Mattia De Sciglio and Kaio Jorge on the treatment table.
Wojciech Szczesny is on the bench after a knock to the chest saw him struggle to breathe during the Sporting match, although tests gave him the all-clear.
Angel Di Maria and Federico Chiesa are rested, so Vlahovic and Milik start together upfront.
Max Allegri also launches another of the youth academy talents, 20-year-old Tommaso Barbieri, on the right flank for his Serie A debut.
Sassuolo are missing captain Domenico Berardi and Mert Muldur, so Nedim Bajrami steps into the trident attack with Andrea Pinamonti and the impressive Laurienté.
The Neroverdi had put together a run of four wins and a draw until the surprise 2-1 stoppage-time defeat to Verona.
They’ve only managed to beat Juventus twice in 20 competitive meetings, 2-1 away in October 2021 and 1-0 at home in October 2015.
Sassuolo: Consigli; Toljan, Erlic, Ruan Tressoldi, Rogerio; Frattesi, Maxime Lopez, Matheus Henrique; Bajrami, Pinamonti, Laurienté
Juventus: Perin; Gatti, Bremer, Danilo; Barbieri, Fagioli, Paredes, Rabiot, Kostic; Milik, Vlahovic
Match statistic
