Napoli miss Jonathan de Guzman, Juan Camilo Zuniga and David Lopez for the trip to Cagliari.
It kicks off on Sunday at 17.00 UK time (16.00 GMT), click here for a match preview.
David Lopez sits out a ban, while De Guzman and Zuniga did not take part in full training today due to injury concerns.
This means Jorginho or Gokhan Inler are likely to step in to midfield.
Napoli miss Jonathan de Guzman, Juan Camilo Zuniga and David Lopez for the trip to Cagliari.
It kicks off on Sunday at 17.00 UK time (16.00 GMT), click here for a match preview.
David Lopez sits out a ban, while De Guzman and Zuniga did not take part in full training today due to injury concerns.
This means Jorginho or Gokhan Inler are likely to step in to midfield.
Napoli squad for Cagliari: Rafael, Andujar, Colombo, Maggio, Mesto, Ghoulam, Strinic, Albiol, Koulibaly, Britos, Henrique, Jorginho, Gargano, Inler, Mertens, Gabbiadini, Insigne, Callejon, Hamsik, Duvan Zapata, Higuain