Juventus start Miralem Pjanic, Paulo Dybala and Cristiano Ronaldo in the Derby della Mole against a Torino side in crisis, led by Andrea Belotti and Simone Verdi.
It kicks off at the Stadio Olimpico Grande Torino at 19.45 GMT.
You can follow the build-up and action as it happens on the LIVEBLOG.
Juventus start Miralem Pjanic, Paulo Dybala and Cristiano Ronaldo in the Derby della Mole against a Torino side in crisis, led by Andrea Belotti and Simone Verdi.
It kicks off at the Stadio Olimpico Grande Torino at 19.45 GMT.
You can follow the build-up and action as it happens on the LIVEBLOG.
The Bianconeri are the only team in Europe’s top five leagues to still be unbeaten in all competition, with 10 wins and three draws.
Miralem Pjanic returns to the starting XI following a muscular problem, while Adrien Rabiot is suspended, so Rodrigo Bentancur is again in midfield.
Gonzalo Higuain is available again following a knock to the head, but he is on the bench in favour of Cristiano Ronaldo and Paulo Dybala.
Alex Sandro is rested in favour of Mattia De Sciglio as left-back, with Aaron Ramsey again on the bench.
Torino are in crisis mode after their Europa League play-off exit and five defeats in the opening 10 Serie A games, their worst start since the 2008-09 campaign, which ended in relegation.
Fans have turned on coach Walter Mazzarri, but President Urbano Cairo has defended the tactician, instead putting the team into a training retreat to prepare for the game.
Iago Falque and Kevin Bonifazi are out injured, with Nicolas Nkoulou suspended, so Lyanco and Bremer are in defence.
Verdi is chosen to support Belotti, but Il Gallo hasn’t scored since September 30, firing blanks in his last four games, although he did accidently score an own goal in the midweek 4-0 defeat to Torino.
Torino have won only one of the last 26 Serie A editions of the Derby della Mole, drawing six and losing the other 19.
That includes nine defeats in the last 10 as hosts, failing to find the net in seven of them.
Torino: Sirigu; Izzo, Bremer, Lyanco; Aina, Baselli, Rincon, Meite, Ansaldi; Verdi, Belotti
Torino bench: Ujkani, Rosati, Lukic, Zaza, Berenguer, Millico, De Silvestri, Djidji, Laxalt
Juventus: Szczesny; Cuadrado, Bonucci, De Ligt, De Sciglio; Bentancur, Pjanic, Matuidi; Bernardeschi; Dybala, Ronaldo
Juventus bench: Pinsoglio, Buffon, Khedira, Ramsey, Douglas Costa, Alex Sandro, Danilo, Higuain, Emre Can, Rugani, Demiral
Ref: Doveri