Sassuolo and Torino go head-to-head for European qualification with two teams packed with young Italian talent.
It kicks off at the Mapei Stadium at 17.00 GMT, click here for a match preview.
Only two points currently separate these sides in sixth and ninth place respectively, while their well-respected Coaches have specialised in getting the best out of homegrown players.
Sassuolo and Torino go head-to-head for European qualification with two teams packed with young Italian talent.
It kicks off at the Mapei Stadium at 17.00 GMT, click here for a match preview.
Only two points currently separate these sides in sixth and ninth place respectively, while their well-respected Coaches have specialised in getting the best out of homegrown players.
Domenico Berardi completes his three-match ban, so will be available again from next week, but joins Emanuele Terranova and Francesco Magnanelli in the stands.
Federico Peluso is only fit for the bench after fracturing his nose against Sampdoria.
Torino have Bruno Peres suspended and the season-long injury crisis continues with Marco Benassi, Joel Obi, Josef Martinez, Alexander Farnerud and Nikola Maksimovic unavailable.
Maxi Lopez leads the attack with Italy Under-21 international Andrea Belotti, resting Fabio Quagliarella for the midweek Coppa Italia showdown with Juventus.
Sassuolo: Consigli; Vrsaljko, Cannavaro, Acerbi, Gazzola; Pellegrini, Missiroli, Laribi; Politano, Floccari, Sansone
Sassuolo bench: Pomini, Pegolo, Longhi, Antei, Biondini, Falcinelli, Peluso, Ariaudo, Fontanesi, Duncan, Defrel, Floro Flores
Torino: Padelli; Bovo, Glik, Moretti; Zappacosta, Acquah, Gazzi, Baselli, Molinaro; Maxi Lopez, Belotti
Torino bench: Castellazzi, Ichazo, Pryyma, Silva, Jansson, Prcic, Vives, Amauri, Quagliarella