Sampdoria and Genoa face off in the rescheduled Derby della Lanterna grudge match.
It kicks off at 17.30 GMT, click here to follow our LIVEBLOG.
The game was originally meant to take place on Saturday night, but was rained off at the Stadio Luigi Ferraris.
These city rivals are accustomed to fighting it out in mid-table, but are in joint sixth place with Inter on 35 points.
Sampdoria and Genoa face off in the rescheduled Derby della Lanterna grudge match.
It kicks off at 17.30 GMT, click here to follow our LIVEBLOG.
The game was originally meant to take place on Saturday night, but was rained off at the Stadio Luigi Ferraris.
These city rivals are accustomed to fighting it out in mid-table, but are in joint sixth place with Inter on 35 points.
Samp won 1-0 earlier this season thanks to Manolo Gabbiadini, who has since moved on to Napoli, while last term Genoa emerged 3-0 victors in the ‘away’ fixture.
This clash is always tense, as reflected by nine red cards over the last 12 editions of the Genoa Derby.
Samuel Eto’o had a muscular problem in Friday’s training session, but this time he is on the bench, as Stefano Okaka returns to the starting XI with Eder and Roberto Soriano.
Luis Muriel made his debut as a substitute last week and scored his first Serie A goal in a year.
Ezequiel Munoz and Fabrizio Cacciatore miss out through injury.
Genoa are fresh from a spectacular 5-2 victory over Hellas Verona, which saw Milan-owned M’Baye Niang break his Serie A duck with a brace.
He starts again with Diego Perotti and Iago Falque.
Sampdoria: Viviano; De Silvestri, Silvestre, Romagnoli, Regini; Acquah, Palombo, Obiang; Soriano; Eder, Okaka
Sampdoria bench: Romero, Mesbah, Duncan, Correa, Bergessio, Rizzo, Muriel, Coda, Djordjevic, Marchionni, Wszolek, Eto’o
Genoa: Perin; Roncaglia, Burdisso, De Maio; Rincon, Kucka, Bertolacci, Edenilson; Falque, Perotti, Niang
Genoa bench: Lamanna, Sommariva, Tambe, Izzo, Lestienne, Bergdich, Pavoletti, Borriello, Mandragora, Laxalt