Fiorentina need a victory to stay top of the table with Inter, but visit Sampdoria who are unbeaten at home with Capocannoniere Eder.
It kicks off at 19.45 GMT, follow all the build-up and action as it happens on our LIVEBLOG.
The Viola appear to have shaken off that blip in form thanks to back-to-back victories over Frosinone, Verona and Lech Poznan.
Fiorentina need a victory to stay top of the table with Inter, but visit Sampdoria who are unbeaten at home with Capocannoniere Eder.
It kicks off at 19.45 GMT, follow all the build-up and action as it happens on our LIVEBLOG.
The Viola appear to have shaken off that blip in form thanks to back-to-back victories over Frosinone, Verona and Lech Poznan.
Inter won 1-0 away to Torino earlier today and Roma beat Lazio 2-0, so a victory is essential if Paulo Sousa’s men are to stay top.
Jakub Blaszczykowski and Marko Bakic are unavailable, but Nikola Kalinic leads the attack with Josip Ilicic, who bagged a brace on Thursday in Poland, and Federico Bernardeschi.
Borja Valero has now recovered from flu symptoms and is passed fit to start.
Sampdoria miss Nenad Krsticic, Andrea Coda and Joaquin Correa, but can rely on the remarkable form of striker Eder, who is Capocannoniere with nine goals.
Luis Muriel and Carlos Carbonero earned recalls for international duty with Colombia this week and will be particularly eager to impress.
Lorenzo De Silvestri – a former Fiorentina player – returns for his first start since suffering a serious knee injury last season.
Samp are unbeaten at Marassi this season with four victories and two stalemates.
Sampdoria: Viviano; De Silvestri, Silvestre, Zukanovic, Pereira; Barreto, Fernando, Soriano; Carbonero, Muriel, Eder
Fiorentina: Tatarusanu; Roncaglia, Gonzalo Rodriguez, Astori, Pasqual, Vecino, Badelj, Borja Valero, Bernardeschi, Ilicic, Kalinic