Maurizio Sarri faces his former club and we should get a fascinating game of football as leaders Napoli host Empoli.
It kicks off at 14.00 GMT, follow the action from all seven Serie A matches on our LIVEBLOG.
The Partenopei need a victory to stay clear at the top, as Juventus are hot on their heels and for the first time have played the earlier kick-off.
The pressure is on and Gonzalo Higuain aims to continue his extraordinary form after 21 goals in 21 rounds.
Maurizio Sarri faces his former club and we should get a fascinating game of football as leaders Napoli host Empoli.
It kicks off at 14.00 GMT, follow the action from all seven Serie A matches on our LIVEBLOG.
The Partenopei need a victory to stay clear at the top, as Juventus are hot on their heels and for the first time have played the earlier kick-off.
The pressure is on and Gonzalo Higuain aims to continue his extraordinary form after 21 goals in 21 rounds.
He is supported by Lorenzo Insigne, Jose Callejon and Marek Hamsik, but ex-Empoli midfielder Mirko Valdifiori is on the bench.
Alberto Grassi picked up a knee injury during his first training session and is out for around three weeks.
Empoli have never really been outplayed by anyone this season and often caused problems against the big clubs, but above all know Sarri’s style very well indeed.
Riccardo Saponara pulls the strings behind Massimo Maccarone and Manuel Pucciarelli, while Leandro Paredes is a big boost with his return to midfield.
Federico Barba is currently undergoing a medical in Stuttgart, so Michele Camporese is thrown into the back four.
Napoli: Reina; Hysaj, Albiol, Koulibaly, Ghoulam; Allan, Jorginho, Hamsik; Callejon, Higuain, Insigne
Empoli: Skorupski; Laurini, Tonelli, Camporese, Mario Rui; Zielinski, Paredes, Croce; Saponara; Pucciarelli, Maccarone