Napoli aim to make history with Dries Mertens, Lorenzo Insigne and Jose Callejon against struggling Cagliari in a game that promises goals.
It kicks off at the Stadio San Paolo at 11.30 UK time (10.30 GMT).
Follow the build-up and action to all EIGHT Serie A games on the LIVEBLOG.
The Partenopei are fresh from a 3-1 Champions League victory over Feyenoord, but above all have a 100 per cent record at the top of the Serie A table.
Napoli aim to make history with Dries Mertens, Lorenzo Insigne and Jose Callejon against struggling Cagliari in a game that promises goals.
It kicks off at the Stadio San Paolo at 11.30 UK time (10.30 GMT).
Follow the build-up and action to all EIGHT Serie A games on the LIVEBLOG.
The Partenopei are fresh from a 3-1 Champions League victory over Feyenoord, but above all have a 100 per cent record at the top of the Serie A table.
Not only would a seventh straight opening win be a new record for Napoli, it’d also be their 12th overall consecutive Serie A victory, including last term.
Goals would seem to be guaranteed this afternoon, because the last nine meetings between these sides have provided 38 goals – an average of 4.2 per game.
Napoli are bound to be confident, having won nine of the last 12 Serie A encounters with Cagliari, drawing the other three.
Mertens leads the way with Callejon and Insigne, as Arkadiusz Milik is out for at least four months following his second ACL surgery in under a year.
Brazilian 18-year-old Leandrinho is on the bench and could get a look-in if Mertens requires rest.
There were concerns over Raul Albiol, who missed the midweek Feyenoord match due to injury, but he’s back in the starting XI.
Cagliari have lost two on the bounce and make this trip with a depleted squad, missing Andrea Cossu, Luca Ceppitelli, Rafael and Gregory van der Wiel.
Defender Fabio Pisacane is also suspended, so 20-year-old Juventus youth product Filippo Romagna gets his first Serie A start, having previously played just one minute of top flight football.
It is above all a reunion for Leonardo Pavoletti, who spent six months at Napoli without scoring a goal and generally limited by injury problems before he made the move to Sardinia this summer.
He has shaken off his latest setback and leads the attack with Marco Sau and Joao Pedro.
Napoli: Reina; Hysaj, Albiol, Koulibaly, Ghoulam; Allan, Jorginho, Hamsik; Callejon, Mertens, Insigne
Napoli bench: Sepe, Rafael, Maggio, Maksimovic, Chiriches, Rui, Rog, Diawara, Zielinski, Ounas, Leandrinho, Giaccherini
Cagliari: Cragno; Padoin, Andreolli, Romagna, Capuano; Ionita, Cigarini, Barella; Joao Pedro; Sau, Pavoletti
Cagliari bench: Crosta, Miangue, Dessena, Faragò, Deiola, Farias, Melchiorri, Giannetti, Molberg