Leaders Milan have Ismael Bennacer back and give Brahim Diaz a chance against Parma, who look to Yann Karamoh and Gervinho.
It kicks off at San Siro at 19.45 GMT, follow all the build-up and action as it happens on the LIVEBLOG.
The Rossoneri need a victory to maintain their five-point lead at the top of the Serie A table, but are without Zlatan Ibrahimovic, Simon Kjaer and Alexis Saelemaekers.
Leaders Milan have Ismael Bennacer back and give Brahim Diaz a chance against Parma, who look to Yann Karamoh and Gervinho.
It kicks off at San Siro at 19.45 GMT, follow all the build-up and action as it happens on the LIVEBLOG.
The Rossoneri need a victory to maintain their five-point lead at the top of the Serie A table, but are without Zlatan Ibrahimovic, Simon Kjaer and Alexis Saelemaekers.
Bennacer returns in midfield with Franck Kessie, while Samu Castillejo, Brahim Diaz and Hakan Calhanoglu support Ante Rebic.
Parma make the trip with Juraj Kucka, who misses out against his former club, so Gaston Brugman takes over in midfield.
Yann Karamoh and Gervinho support Andreas Cornelius.
Milan: G Donnarumma; Calabria, Gabbia, Romagnoli, Theo Hernandez; Kessie, Bennacer; Castillejo, Brahim Diaz, Calhanoglu; Rebic
Parma: Sepe; Iacoponi, Osorio, Bruno Alves, Gagliolo; Hernani, Brugman, Kurtic; Karamoh, Gervinho; Cornelius
Ref: Fourneau