Milan rely on Patrick Cutrone and Hakan Calhanoglu against Sampdoria’s Duvan Zapata and Fabio Quagliarella in a showdown for sixth place.
It kicks off at 19.45 GMT, follow the build-up and action as it happens on the LIVEBLOG.
The top six teams go into Europe next season and a victory tonight would put Milan level in sixth place with Sampdoria.
Milan rely on Patrick Cutrone and Hakan Calhanoglu against Sampdoria’s Duvan Zapata and Fabio Quagliarella in a showdown for sixth place.
It kicks off at 19.45 GMT, follow the build-up and action as it happens on the LIVEBLOG.
The top six teams go into Europe next season and a victory tonight would put Milan level in sixth place with Sampdoria.
Gennaro Gattuso’s men have made a remarkable climb back up the standings and are unbeaten in nine competitive games, but will they be able to handle the strain of Thursday’s 3-0 Europa League win over Ludogorets with minimal squad rotation?
Nikola Kalinic and Andrea Conti are out of action, while Franck Kessie is suspended, which inevitably changes the balance of the midfield.
Riccardo Montolivo is chosen to come in with Lucas Biglia and Jack Bonaventura, and the now traditional front three of Suso, Cutrone and Calhanoglu.
Ricardo Rodriguez makes his first start since recovering from injury, having converted a penalty in Bulgaria midweek.
Sampdoria are unbeaten in five rounds and conceded only one goal in their last three matches.
Despite turning 35 in January, Quagliarella has been an inspirational figure with 17 Serie A goals this season – more than Napoli’s Dries Mertens – and he’s supported by Duvan Zapata and Gaston Ramirez.
Lucas Torreira is also one to be wary of in midfield, particularly from free kicks.
The Blucerchiati have won their last two Serie A meetings with Milan.
Milan: G Donnarumma; Calabria, Romagnoli, Bonucci, Ricardo Rodriguez; Montolivo, Biglia, Bonaventura; Suso, Cutrone, Calhanoglu
Milan bench: A Donnarumma, Guarnone, Abate, Antonelli, Gomez, Musacchio, C Zapata, Locatelli, Mauri, Borini, Andre Silva, Tsadjout
Sampdoria: Viviano; Bereszynski, Silvestre, Ferrari, Murru; Barreto, Torreira, Linetty; Ramirez; Duvan Zapata, Quagliarella
Sampdoria bench: Tozzo, Krapikas, Andersen, Regini, Strinic, Ercolano, Capezzi, Tessiore, Verre, Álvarez, Caprari, Kownacki