Morgan De Sanctis is out and Francesco Totti in as Roma take on Manchester City in the Champions League.
It kicks off at the Etihad at 19.45 UK time (18.45 GMT).
Morgan De Sanctis is out and Francesco Totti in as Roma take on Manchester City in the Champions League.
It kicks off at the Etihad at 19.45 UK time (18.45 GMT).
The Giallorossi won their opening tie 5-1 against CSKA Moscow and still have a 100 per cent record in six games in all competition this season.
Coach Rudi Garcia has injury problems to contend with, as Daniele De Rossi, Leandro Castan, Davide Astori and Kevin Strootman are out of action.
Goalkeeper De Sanctis needed a late fitness test and failed, so Lukasz Skorupski gets a rare go between the sticks instead.
Totti is given a starting spot just days after his 38th birthday, joining ex-Arsenal striker Gervinho and Alessandro Florenzi.
Juan Manuel Iturbe, who was out for two weeks with a muscular problem, is back on the bench.
Ashley Cole and ex-Manchester City full-back Douglas Maicon also start.
Manchester City lost their first Champions League group game away to Bayern Munich, so the pressure is already piling on them to deliver full points tonight.
The Premier League holders are without Samir Nasri, while ex-Fiorentina pair Stevan Jovetic and Matija Nastasic are struggling with muscular problems.
Joe Hart, Martin Demichelis and Gael Clichy are picked ahead of Willy Caballero, Eliaquim Mangala and Aleksandar Kolarov, while Edin Dzeko and Sergio Aguero lead the attack.
Manchester City don’t have a good record with Italian clubs, winning only one of their last seven meetings and losing four.
Totti has never scored on English soil and Roma famously lost a Champions League tie 7-1 to Manchester United in April 2007.
Manchester City: Hart; Zabaleta, Kompany, Demichelis, Clichy; Navas, Fernandinho, Yaya Toure, Silva; Dzeko, Aguero
Man City bench: Caballero, Sagna, Mangala, Kolarov, Milner, Lampard, Jovetic
Roma: Skorupski; Maicon, Manolas, Yanga-Mbiwa, Cole; Pjanic, Keita, Nainggolan; Florenzi, Totti, Gervinho
Roma bench: Curci, Torosidis, Ljajic, Holebas, Paredes, Destro