Napoli miss Lorenzo Insigne, so start Dries Mertens, Chucky Lozano and Fabian Ruiz in their Champions League showdown with Mohamed Salah’s Liverpool.
It kicks off at Anfield at 20.00 GMT and they are separated by one point at the top of their group.
You can follow the build-up and action as it happens from this game and Slavia Prague-Inter on the LIVEBLOG.
Napoli miss Lorenzo Insigne, so start Dries Mertens, Chucky Lozano and Fabian Ruiz in their Champions League showdown with Mohamed Salah’s Liverpool.
It kicks off at Anfield at 20.00 GMT and they are separated by one point at the top of their group.
A win would qualify either of these two sides for the Round of 16, although they could both go through tonight if RB Salzburg fail to beat Genk.
It comes at a crisis point for Napoli, who are without a win in their last six competitive games and locked under a press silence after the club imposed heavy fines for the team ‘mutiny’ against a training retreat last month.
Captain Lorenzo Insigne and striker Arkadiusz Milik didn’t make the trip due to injury, while Faouzi Ghoulam and Kevin Malcuit are long-term absentees.
Fabian Ruiz and Mario Rui are not 100 per cent fit, but both are passed ready for the starting XI.
The big surprise is that Jose Callejon – who is captain in Insigne’s absence – is dropped in order to use right-back Giovanni Di Lorenzo in a more advanced role.
Carlo Ancelotti starts Hirving ‘Chucky’ Lozano upfront with Dries Mertens, despite late reports Fernando Llorente was being tested upfront.
Kostas Manolas returns to the defence, but Nikola Maksimovic is on the right in what is effectively a very defensive formation down that side.
Mohamed Salah has shaken off an ankle problem to start for Liverpool with Roberto Firmino and Sadio Mane.
Alisson Becker revealed he had negotiations for a move to Napoli before choosing Liverpool, but it would’ve been “a difficult situation” considering the rivalry with Roma.
Nathaniel Clyne, Joel Matip and Xherdan Shaqiri are out of action.
Last season, Napoli’s 1-0 loss here proved decisive for Liverpool’s progress and they went on to win the Champions League, thanks largely to Alisson’s last-gasp save on Milik.
The Partenopei won both their recent meetings with Liverpool at the Stadio San Paolo.
Liverpool: Alisson; Gomez, Van Dijk, Lovren, Robertson; Fabinho, Milner, Henderson; Salah, Firmino, Mane
Liverpool bench: Adrian, Wijnaldum, Oxlade-Chamberlain, Lallana, Shaqiri, Origi, Alexander-Arnold
Napoli: Meret; Maksimovic, Manolas, Koulibaly, Mario Rui; Di Lorenzo, Allan, Zielinski, Fabian Ruiz; Mertens, Lozano
Napoli bench: Ospina, Luperto, Elmas, Gaetano, Callejon, Llorente, Younes
Ref: Del Cerro Grande (ESP)