Inter reshuffle yet again with Mauro Icardi, Stevan Jovetic and Ivan Perisic for their difficult trip to Lazio.
It kicks off at 19.45 UK time (18.45 GMT), follow all the build-up and action as it happens on our LIVEBLOG.
The Nerazzurri need a victory to consolidate fourth place after Fiorentina’s 0-0 draw with Chievo, but above all keep in touch with Roma in third ahead of their visit to Genoa tomorrow evening.
Inter reshuffle yet again with Mauro Icardi, Stevan Jovetic and Ivan Perisic for their difficult trip to Lazio.
It kicks off at 19.45 UK time (18.45 GMT), follow all the build-up and action as it happens on our LIVEBLOG.
The Nerazzurri need a victory to consolidate fourth place after Fiorentina’s 0-0 draw with Chievo, but above all keep in touch with Roma in third ahead of their visit to Genoa tomorrow evening.
Roberto Mancini faces his former club and above all Simone Inzaghi, who was both his teammate and player at Lazio, but they meet for the first time as coaching colleagues.
Adem Ljajic is the only absentee for Inter, but Mancini makes yet more changes with Gary Medel and Geoffrey Kondogbia in midfield.
Marcelo Brozovic is pushed into a more advanced role with Jovetic and Perisic to support hitman Icardi.
Lazio, on the other hand, are in their now habitual injury crisis, missing Alessandro Matri, Marco Parolo, Stefan Radu, Ricardo Kishna and Stefan de Vrij.
Miroslav Klose has shaken off a knock to start with Keita Balde Diao and Inter transfer target Antonio Candreva.
Lucas Biglia is another player heavily linked with a summer move to San Siro and he pulls the strings in midfield.
Lazio: Marchetti; Basta, Bisevac, Gentiletti, Konko; Onazi, Biglia, Lulic; Candreva, Klose, Keita
Lazio bench: Berisha, Guerrieri, Mauricio, Hoedt, Patric, Braafheid, Milinkovic-Savic, Cataldi, Morrison, Mauri, Felipe Anderson
Inter: Handanovic; Nagatomo, Miranda, Murillo, D'Ambrosio; Medel, Kondogbia; Brozovic, Jovetic, Perisic; Icardi
Inter bench: Carrizo, Berni, Juan Jesus, Santon, Telles, Gnoukouri, Felipe Melo, Biabiany, Eder, Palacio, Manaj