It’s first against second with only one point separating them, as Fiorentina host Roma with Mohamed Salah starting.
It kicks off at the Stadio Franchi at 17.00 GMT, follow the action from this and Lazio-Torino on our LIVEBLOG.
There are so many layers to this clash, especially as they faced off last season in the Europa League and Coppa Italia too.
It’s first against second with only one point separating them, as Fiorentina host Roma with Mohamed Salah starting.
It kicks off at the Stadio Franchi at 17.00 GMT, follow the action from this and Lazio-Torino on our LIVEBLOG.
There are so many layers to this clash, especially as they faced off last season in the Europa League and Coppa Italia too.
The tension is palpable in Tuscany with Viola fans accompanying the team bus in a moped motorcade to the stadium and 5,000 whistles prepared to harass Salah.
It’s his first time back in Florence since refusing to extend his loan spell from Chelsea, a decision that is still being debated by FIFA with his old club requesting a six-month ban for breach of contract.
Rudi Garcia isn’t shying away from that fiery atmosphere and puts Salah in from the start.
Francesco Totti, Seydou Keita and Kevin Strootman are still injured, while Edin Dzeko and Gervinho complete the trident, moving Alessandro Florenzi to right-back again.
Fiorentina miss only Marko Bakic and Gilberto, but Marcos Alonso failed a fitness test and Davide Astori faces his former club.
Nikola Kalinic has been a sensation up front and is supported by Josip Ilicic, Federico Bernardeschi, Borja Valero and Jakub Blaszczykowski.
Roma have won two of their last three Serie A visits to the Stadio Franchi, drawing 1-1 last season.
Fiorentina: Tatarusanu, Roncaglia, Gonzalo Rodriguez, Astori, Blaszczykowski, Vecino, Badelj, Bernardeschi, Borja Valero, Ilicic, Kalinic
Fiorentina bench: Lezzerini, Sepe, Tomovic, Rebic, Mati Fernandez, Suarez, Verdù, Rossi, Pasqual, Babacar
Roma: Szczesny; Florenzi, Manolas, Rudiger, Digne; Pjanic, De Rossi, Nainggolan; Salah, Dzeko, Gervinho
Roma bench: De Sanctis, Maicon, Torosidis, Castan, Gyömbér, Emerson, Uçan, Vainqueur, Iturbe, Ponce, Sadiq, Falque