Cagliari hope Leonardo Pavoletti can continue his scoring record against Sampdoria in the early Saturday kick-off.
It begins at 17.00 GMT, follow all the build-up and action as it happens from this game and Juventus–Inter on the LIVEBLOG.
The Sardinians are looking to get back on track following a surprise Coppa Italia exit to Pordenone and draw with Bologna.
Cagliari hope Leonardo Pavoletti can continue his scoring record against Sampdoria in the early Saturday kick-off.
It begins at 17.00 GMT, follow all the build-up and action as it happens from this game and Juventus-Inter on the LIVEBLOG.
The Sardinians are looking to get back on track following a surprise Coppa Italia exit to Pordenone and draw with Bologna.
Samp are also unpredictable, strong on home turf and stuttering on their travels, but last week lost their perfect Marassi record against Lazio.
Nicolò Barella is suspended for the hosts, with Rafael not 100 per cent fit and the goalkeeper pulled out in the warm-up to make way for Alessio Cragno.
Pavoletti has an excellent scoring record against Sampdoria, putting three goals past them in their last three meetings, along with two assists.
The Blucerchiati welcome Ivan Strinic back at least for a spot on the bench, but ex-Cagliari man Nicola Murru gets the nod instead.
Gaston Ramirez supports Fabio Quagliarella and Duvan Zapata, but Karol Linetty is injured.
This fixture has not been a scoreless draw since 2010.
Cagliari: Cragno; Romagna, Ceppitelli, Andreolli; Faragò, Dessena, Cigarini, Ionita, Padoin; Joao Pedro; Pavoletti
Sampdoria: Viviano; Bereszynski, Silvestre, Ferrari, Murru; Barreto, Torreira, Praet; Ramirez; Quagliarella, Duvan Zapata