The pressure is on Inter with Lautaro Martinez, Edin Dzeko and Denzel Dumfries starting, while Lecce have Samuel Umtiti back, but lose Federico Baschirotto to a ban.
It kicks off at San Siro at 17.00 GMT, you can follow all the build-up and action as it happens from today’s Serie A games including Roma-Juventus on the LIVEBLOG.
The Nerazzurri are feeling the strain after a surprise defeat to Bologna, while Lazio’s victory away to Napoli means a win is essential to retain second place and break away from rivals Milan.
Joaquin Correa is still out of action, with Federico Dimarco and Milan Skriniar not risked after muscular issues, so Robin Gosens and Matteo Darmian step in.
Dzeko is preferred to Romelu Lukaku as partner to Lautaro Martinez.
Lecce also had a shock defeat last week, 1-0 at home to Sassuolo, but remain comfortably mid-table.
Free-scoring defender Baschirotto sits out a ban, with Lameck Banda on compassionate leave, Kastriot Dermaku, Joel Voelkerling Persson and Marin Pongracic injured.
The good news for coach Marco Baroni is the return of ex-Barcelona defender Samuel Umtiti in defence and Federico Di Francesco upfront.
Inter: Onana; Darmian, Acerbi, Bastoni; Dumfries, Barella, Calhanoglu, Mkhitaryan, Gosens; Lautaro Martinez, Dzeko
Lecce: Falcone; Gendrey, Umtiti, Tuia, Pezzella; Gonzalez, Hjulmand, Maleh; Strefezza, Ceesay, Di Francesco
Player statistic
| Henrikh Mkhitaryan (Assist: Nicolò Barella) |
 |
29' |
| Lautaro Martínez (Assist: Denzel Dumfries) |
|
52' |
Match statistic
