Roma star Paulo Dybala is ready to start against his former club Juventus at the Stadio Olimpico tonight, while Max Allegri will be looking to Dusan Vlahovic and Angel Di Maria.
It kicks off at 19.45 GMT.
The Giallorossi are without the inured Ebrima Darboe and Ola Solbakken, but Dybala is fit to start against his ex-club. The Argentinean striker delivered an assist in a 1-1 draw in the reverse fixture in Turin, his first match against Juventus as an opponent since leaving last summer.
The only doubt for Mourinho appears to be on the right flank where Rick Karsdorp is favourite over Nicola Zalewski.
Juventus have travelled to the Olimpico without Arek Milik and Mattia De Sciglio. This means Juan Cuadrado will start on the right in a 3-5-1-1 system with Vlahovic and Di Maria up front.
Paul Pogba and Federico Chiesa are available but are both expected to start on the bench and be involved in the second half.
Roma vs. Juventus – probable line-ups
Roma (3-4-1-2): Rui Patricio; Mancini, Smalling, Ibanez; Karsdorp, Cristante, Matic, Spinazzola; Pellegrini; Dybala, Abraham.
Juventus (3-5-2): Szczesny; Danilo, Bermer, Alex Sandro; Cuadrado, Fagioli, Locatelli, Rabiot, Kostic; Vlahovic, Di Maria.