Fresh off the back of their European success, Milan are hungry to bounce back in Serie A against Lecce after a tough few weeks.
The match between the Puglian outfit and the Rossoneri kicks off at 14.00 UK time at the Stadio Via del Mare in Lecce.
Lecce picked up a few key victories early in the season, beating Lazio, Salernitana and Genoa, but have started to slow down in recent weeks, failing to find victory in their last six league outings.
The Salentini cannot count on Pontus Almqvist and Jeppe Corfitzen, both of whom are sidelined with injuries.
Milan have been in poor form since the October international break, finding just one point in their last three Serie A matches, but they responded in definitive fashion in their return clash with Paris Saint-Germain in the Champions League, edging out a 2-1 win.
The Rossoneri are without the injured Marco Sportiello, Simon Kjaer, Pierre Kalulu, Ismael Bennacer and Marco Pellegrino. Christian Pulisic is unlikely to start as he finishes his recovery from a muscle issue.
Probable line-ups for Lecce vs Milan
Lecce (4-3-3): Falcone; Gendrey, Baschirotto, Pongracic, Dorgu; Kaba, Ramadani, Rafia; Strefezza, Krstovic, Banda.
Milan (4-3-3): Maignan; Calabria, Tomori, Thiaw, Theo Hernandez; Loftus-Cheek, Krunic, Reijnders; Chukwueze, Giroud, Leao.