Napoli have major injury problems going into the trip to Udinese, as after Kvicha Kvaratskhelia, now Giacomo Raspadori is also struggling.
It kicks off at the Bluenergy Stadium on Monday at 19.45 UK time (18.45 GMT).
The Partenopei still need points to qualify for Europe next season, while Udinese are desperate to avoid relegation into Serie B.
Kvaratskhelia was already unlikely to make the trip to Udine after suffering from muscular issues in training.
The natural replacement in the trident attack was Raspadori, but now the Italian is also struggling after spraining his left ankle during yesterday’s session.
Raspadori adds to Napoli problems
Leander Dendoncker, who has barely featured since arriving on loan in January, is also out of action with a muscular twinge, while Piotr Zielinski and Pierluigi Gollini are still sidelined.
The good news for coach Francesco Calzona is that Matteo Politano and Juan Jesus returned to full training with the rest of the group.