Napoli have a notoriously poor record away to Udinese, but Lorenzo Insigne starts despite running a temperature.
It kicks off at 17.00 GMT, follow the build-up and action on the LIVEBLOG.
The Partenopei have always had problems in the Friuli region, not winning here since 2007 with just four draws from eight attempts.
Both teams have found the net in three of their last four encounters.
Napoli have a notoriously poor record away to Udinese, but Lorenzo Insigne starts despite running a temperature.
It kicks off at 17.00 GMT, follow the build-up and action on the LIVEBLOG.
The Partenopei have always had problems in the Friuli region, not winning here since 2007 with just four draws from eight attempts.
Both teams have found the net in three of their last four encounters.
Maurizio Sarri has Raul Albiol back after over a month out, but he’s only on the bench, so Vlad Chiriches gets the nod.
Jose Callejon has shaken off flu symptoms, but passed them on to teammate Insigne, who is able to start despite feeling feverish.
Emanuele Giaccherini had hoped to get his first start in a Napoli jersey.
Dries Mertens takes the False 9 role, as Manolo Gabbiadini and Arkadiusz Milik are injured.
In the circumstances, Napoli could really do with having Duvan Zapata back in their ranks, but he lines up for Udinese during his two-year loan spell.
Emil Hallfredsson, Adalberto Penaranda, Francesco Lodi, Panagiotis Kone and Ewandro are out of action.
The playing conditions are very difficult indeed, as the Friuli region has been subjected to heavy thunderstorms all day and there is flooding in the area.
The pitch of the newly-reconstructed Dacia Arena appears to be holding up, though.
Udinese: Karnezis; Widmer, Danilo, Wague, Felipe; Fofana, Kums, Badu; Matos, Duvan Zapata, Thereau
Napoli: Reina; Hysaj, Chiriches, Koulibaly, Ghoulam; Allan, Diawara, Hamsik; Callejon, Mertens, Insigne