Inter target a third consecutive victory in their trip to a decimated Sassuolo, a side they’ve lost the last three meetings with.
It kicks off at the Mapei Stadium at 11.30 GMT, follow the build-up and action on the Liveblog.
The Nerazzurri seem to be finding their feet under new Coach Stefano Pioli, winning three of their last four games between Serie A and the Europa League.
Inter target a third consecutive victory in their trip to a decimated Sassuolo, a side they’ve lost the last three meetings with.
It kicks off at the Mapei Stadium at 11.30 GMT, follow the build-up and action on the Liveblog.
The Nerazzurri seem to be finding their feet under new Coach Stefano Pioli, winning three of their last four games between Serie A and the Europa League.
However, they are without an away success since the 2-0 at Empoli on September 21, managing seven defeats and a draw – which was at San Siro in the Milan Derby.
Gary Medel and Assane Gnoukouri are injured, while Stevan Jovetic is left out amid reports of a January move to Fiorentina.
Pioli sticks with his new three-man defence, using Antonio Candreva, Ivan Perisic and Joao Mario to support hitman Mauro Icardi in a 3-4-2-1 formation.
Sassuolo have precious few options available for Coach Eusebio Di Francesco, who on top of an injury crisis also has Federico Peluso suspended.
The absentee list is massive, including Domenico Berardi, Alfred Duncan, Matteo Politano, Francesco Magnanelli, Paolo Cannavaro, Davide Biondini, Marcello Gazzola and Timo Letschert.
Gregoire Defrel leads the attack with Stefano Ricci and Antonino Ragusa, but Cristian Dell’Orco has a baptism of fire against these Inter forwards.
Lorenzo Pellegrini is passed fit to start, but Simone Missiroli and Emanuele Terranova are only ready for the bench.
These two clubs have never shared the spoils, as Inter won their first three meetings – including two 7-0 results – followed by three consecutive Sassuolo victories.
The last two editions of this fixture in Reggio-Emilia both ended 3-1.
Sassuolo: Consigli; Lirola, Antei, Acerbi, Dell’Orco; Pellegrini, Sensi, Mazzitelli; Ricci, Defrel, Ragusa
Sassuolo bench: Pomini, Pegolo, Missiroli, Terranova, Erlic, Franchini, Adjapong, Pierini, Iemmello, Matri
Inter: Handanovic; D’Ambrosio, Miranda, Murillo; Candreva, Brozovic, Felipe Melo, Ansaldi; Joao Mario, Perisic; Icardi
Inter bench: Carrizo, Andreolli, Ranocchia, Santon, Biabiany, Nagatomo, Kondogbia, Banega, Eder, Palacio, Gabriel Barbosa