Napoli are taking no chances against Verona in the Coppa Italia, starting Gonzalo Higuain and Dries Mertens.
It kicks off at the Stadio San Paolo at 18.00 GMT and will be decided after 90 minutes, extra time or penalties.
The winners go through to face Inter in the quarter-finals.
Maurizio Sarri fields a relatively strong line-up with star striker Higuain leading Mertens and Omar El Kaddouri, though there are big changes in midfield and defence.
Pepe Reina is given the gloves despite it being a Cup competition.
Napoli are taking no chances against Verona in the Coppa Italia, starting Gonzalo Higuain and Dries Mertens.
It kicks off at the Stadio San Paolo at 18.00 GMT and will be decided after 90 minutes, extra time or penalties.
The winners go through to face Inter in the quarter-finals.
Maurizio Sarri fields a relatively strong line-up with star striker Higuain leading Mertens and Omar El Kaddouri, though there are big changes in midfield and defence.
Pepe Reina is given the gloves despite it being a Cup competition.
Verona are without a single Serie A victory all season and sit bottom of the table, but hope to turn things around in the Coppa Italia.
Coach Gigi Del Neri rotates his squad and hitman Luca Toni isn’t even on the bench.
Mohamed Fares returns after a lengthy injury lay-off, but Juanito Gomez Taleb is sidelined.
Napoli: Reina; Maggio, Chiriches, Koulibaly, Strinic; Allan, Valdifiori, David Lopez; El Kaddouri, Higuain, Mertens
Napoli bench: Gabriel, Rafael, Hysaj, Henrique, Callejon, Jorginho, Hamsik, Dezi, Insigne, Ghoulam, Luperto, Chalobah
Verona: Coppola; Bianchetti, Moras, Helander, Pisano; Checchin, Hallfredsson; Jankovic, Siligardi, Fares; Wszolek
Verona bench: Rafael, Gollini, Greco, Zaccagni, Sala, Tupta, Winck, Guglielmelli