Napoli are Winter Champions and must beat Sassuolo – one of only two sides they lost to this season – to stay top of Serie A.
It kicks off at 19.45 GMT, follow the action as it happens from all today’s games on our LIVEBLOG.
The Partenopei leapfrogged Inter to take the Winter Crown and now begin the second half of the campaign.
Napoli are Winter Champions and must beat Sassuolo – one of only two sides they lost to this season – to stay top of Serie A.
It kicks off at 19.45 GMT, follow the action as it happens from all today’s games on our LIVEBLOG.
The Partenopei leapfrogged Inter to take the Winter Crown and now begin the second half of the campaign.
Maurizio Sarri lost his opening match, a 2-1 result at Sassuolo, but that and Bologna’s 3-2 were the only defeats suffered this season between Serie A, the Europa League and Coppa Italia.
The last time Napoli went top of the table, they lost to Bologna the very next round, so tonight it is above all a test of their mentality.
It’s also worth noting Sassuolo are the only side who haven’t lost to the top five this season and shocked Inter last week at San Siro.
Nathaniel Chalobah is the only absentee for Napoli on compassionate leave, but Lorenzo Insigne returns to the trident with Jose Callejon and Capocannoniere Gonzalo Higuain.
Pipita has remarkably scored 18 goals in 19 Serie A rounds.
Kalidou Koulibaly is rested, so Vlad Chiriches partners Raul Albiol at centre-back.
Sassuolo are not to be underestimated, even if they are missing suspended Domenico Berardi and hometown hero Paolo Cannavaro.
Diego Falcinelli gets the nod in attack with Nicola Sansone and Matteo Politano.
Napoli: Reina; Hysaj, Albiol, Chiriches, Ghoulam; Allan, Jorginho, Hamsik; Callejon, Higuain, Insigne
Sassuolo: Consigli; Vrsaljko, Ariaudo, Acerbi, Peluso; Missiroli, Magnanelli, Duncan; Politano, Falcinelli, Sansone