Gonzalo Higuain is out for revenge as Napoli reshuffle against Lazio under pressure at the San Paolo.
It kicks off at 19.45 UK time (18.45 GMT), follow the build-up and action as it happens on our LIVEBLOG.
Maurizio Sarri finally got his first victory on the Partenopei bench and did it in style, demolishing Club Brugge 5-0 in the Europa League on Thursday.
In Serie A he has just two draws from three rounds, so this is already a must-win fixture.
Gonzalo Higuain is out for revenge as Napoli reshuffle against Lazio under pressure at the San Paolo.
It kicks off at 19.45 UK time (18.45 GMT), follow the build-up and action as it happens on our LIVEBLOG.
Maurizio Sarri finally got his first victory on the Partenopei bench and did it in style, demolishing Club Brugge 5-0 in the Europa League on Thursday.
In Serie A he has just two draws from three rounds, so this is already a must-win fixture.
The squad has a point to prove after last season’s 4-2 defeat handed third place to Lazio and with it the chance to get into the Champions League.
Higuain missed a penalty in that game and arguably still hasn’t quite recovered his confidence.
Pipita is supported by Lorenzo Insigne and Jose Callejon, while Marek Hamsik takes a deeper role.
Stefano Pioli has a long list of absentees, including Antonio Candreva, Miroslav Klose, Stefan de Vrij, Lucas Biglia and Ravel Morrison.
Alessandro Matri bagged a brace on his debut last week and starts in attack with Keita Balde Diao and Stefano Mauri.
Napoli: Reina; Hysaj, Albiol, Koulibaly, Ghoulam; Allan, Jorginho, Hamsik; Insigne; Higuain, Callejon
Napoli bench: Gabriel, Rafael, Maggio, Strinic, Henrique, Chiriches, Valdifiori, David Lopez, El Kaddouri, Chalobah, Mertens, Gabbiadini
Lazio: Marchetti; Basta, Mauricio, Hoedt, Radu; Parolo, Onazi, Lulic; Mauri, Matri, Keita
Lazio bench: Berisha, Guerrieri, Konko, Gentiletti, Patric, Braafheid, Cataldi, Oikonomidis, Onazi, Milinkovic-Savic, Kishna, Felipe Anderson