Napoli could be saying goodbye to many famous faces, but Crotone simply have to win and hope for the best to stay in Serie A.
It kicks off at 17.00 UK time (16.00 GMT).
Follow the build-up and action as it happens from all NINE Serie A games on the LIVEBLOG.
Napoli could be saying goodbye to many famous faces, but Crotone simply have to win and hope for the best to stay in Serie A.
It kicks off at 17.00 UK time (16.00 GMT).
Follow the build-up and action as it happens from all NINE Serie A games on the LIVEBLOG.
The Partenopei missed out on the Scudetto and must now look to the future, with Pepe Reina and Cristian Maggio leaving, but big question marks over Marek Hamsik, Jose Callejon, Jorginho, Dries Mertens, Kalidou Koulibaly and Coach Maurizio Sarri.
If they were to win, Napoli would become the first Serie A side in history to go over 90 points and still not win the Scudetto.
There is plenty at stake for Crotone, who are in the bottom three entering the final 90 minutes of the season.
They achieved an amazing comeback to escape the drop on the last day a year ago, can they do it again?
Vlad Chiriches is out injured, but Sarri decides to shake things up a bit in the final round with Marek Hamsik and Dries Mertens rested in favour of Piotr Zielinski and Arkadiusz Milik.
Crotone miss Ahmad Benali and Ante Budimir, but rely again on impressive young striker Simy, flanked by Marcello Trotta and Andrea Nalini.
Rolando Mandragora in midfield wants to celebrate his first senior Italy call-up under new Coach Roberto Mancini.
Crotone need to win and hope one of Chievo, Cagliari, Udinese and SPAL lose.
They could also survive with a stalemate as long as SPAL lose to Sampdoria.
Napoli have previously won all three Serie A meetings with Crotone, home and away.
Napoli: Reina; Hysaj, Albiol, Koulibaly, Mario Rui; Allan, Jorginho, Zielinski; Callejon, Milik, Insigne
Crotone: Cordaz; Sampirisi, Ceccherini, Capuano, Martella; Barberis, Mandragora, Rohden; Trotta, Simy, Nalini
Ref: Banti