Lazio and Fiorentina face off for Europe with Felipe Anderson against Mohamed Salah.
It kicks off at 18.00 GMT, click here to follow our LIVEBLOG.
These are the two form teams in Serie A at the moment and both coming off three consecutive victories.
If Lazio win, they will catch Napoli in third place after the Partenopei were held to a 2-2 draw by Inter last night.
Lazio and Fiorentina face off for Europe with Felipe Anderson against Mohamed Salah.
It kicks off at 18.00 GMT, click here to follow our LIVEBLOG.
These are the two form teams in Serie A at the moment and both coming off three consecutive victories.
If Lazio win, they will catch Napoli in third place after the Partenopei were held to a 2-2 draw by Inter last night.
Stefano Pioli has to do without Senad Lulic, Abdoulay Konko, Filip Djordjevic, Bruno Pereirinha, Santiago Gentiletti and the suspended Marco Parolo.
Antonio Candreva has recovered after crashing into a metal barrier during his goal celebration against Palermo, while Stefano Mauri can play despite dislocating his toe last week.
Miroslav Klose and Mauri flank Brazilian talent Felipe Anderson, who is key to their success this season.
Fiorentina have discovered their own hero in Mo Salah, who has made a stunning impact since arriving on loan from Chelsea in the Juan Cuadrado deal.
He starts with Alessandro Diamanti and Josip Ilicic in what is basically a strikerless system, as Mario Gomez, Khouma Babacar, Federico Bernardeschi and Ciprian Tatarusanu are ruled out.
Alberto Aquilani is suspended in midfield.
Lazio: Marchetti; Basta, De Vrij, Mauricio, Radu; Cataldi, Biglia; Candreva, Mauri, Felipe Anderson; Klose
Lazio bench: Berisha, Strakosha, Ciani, Braafheid, Ederson, Keita, Onazi, Ledesma, Cana, Perea, Cavanda, Novaretti
Fiorentina: Neto, Savic, Basanta, Tomovic, Pasqual, Kurtic, Mati Fernandez, Badelj, Diamanti, Ilicic, Salah
Fiorentina bench: Lezzerini, Rosati, Gonzalo Rodriguez, Richards, Vargas, Pizarro, Gilardino, Joaquin, Borja Valero, Alonso, Lazzari, Rosi