Atalanta look to Ruslan Malinovskyi, Aleksei Miranchuk and Duvan Zapata against Genoa, knowing a win here guarantees them a top four finish.
It kicks off at the Stadio Luigi Ferraris, also known as Marassi, at 14.00 UK time (13.00 GMT).
La Dea have a superior head-to-head record with Juventus, so three points here would put them beyond reach in a Champions League spot.
Gian Piero Gasperini visits his old stomping ground and relies on the creativity of Malinovskyi and Miranchuk supporting Duvan Zapata.
Pierluigi Gollini returns from suspension to take the gloves.
Genoa have already secured their Serie A status with a 2-0 win away to Bologna midweek, so can play without pressure.
Domenico Criscito, Milan Badelj, Davide Biraschi, Gianluca Scamacca and Lennart Czyborra are on the treatment table.
Cristian Zapata won’t be marking his cousin Duvan, as coach Davide Ballardini takes advantage of the situation to completely rotate his squad.
Genoa: Marchetti; Radovanovic, Masiello, Onguene; Ghiglione, Zajc, Rovella, Melegoni, Cassata; Destro, Pjaca
Atalanta: Gollini; Toloi, Romero, Djimsiti; Hateboer, De Roon, Freuler, Gosens; Malinovskyi, Miranchuk; Duvan Zapata
Ref: Marinelli