Gianluca Scamacca is back in the Atalanta squad, but only fit for the bench, as Charles De Ketelaere and Ademola Lookman lead the attack away to Sporting CP.
It kicks off at the Estadio Alvalade at 17.45 UK time (16.45 GMT).
La Dea started their Europa League campaign with a 2-0 win over Polish champions Rakow and are fresh from a frustrating 0-0 draw with Juventus in Serie A, having dominated the game.
El Bilal Toure is still out of action, but Scamacca is recovering ahead of schedule for a return to the bench after almost a month out.
Curiously, Atalanta played the Champions League quarter-final against PSG in Lisbon in August 2020, when they were leading until conceding two very late goals.
Sporting won 2-1 away to Sturm Graz in their opening fixture, so this is a head-to-head for the top spot in this group.
Jerry St. Juste and Trincao are out of action, while captain Sebastian Coates is only fit for the bench, but former Lecce midfielder Morten Hjulmand starts.
Sporting: Adan; Diomande, Goncalo Inacio, Matheus Reis; Fresneda, Hjulmand, Morita, Nuno Santos; Pedro Goncalves, Gyokeres; Paulinho
Sporting bench: Israel, Diogo Pinto, Coates, Edwards, Luis Neto, Dario Essugo, Catamo, Daniel Braganca, Ricardo Esgaio, Eduardo Quaresma, Tiago Ferreira, Rodrigo Ribeiro
Atalanta: Musso; Scalvini, Djimsiti, Kolasinac; Zappacosta, De Roon, Ederson, Ruggeri; Koopmeiners; De Ketelaere, Lookman
Atalanta bench: Carnesecchi, Rossi, Toloi, Holm, Palomino, Pasalic, Muriel, Scamacca, Bakker, Adopo, Hateboer, Miranchuk
Ref: Hernandez (ESP)
Player statistic
33' | Giorgio Scalvini | |||
43' | Matteo Ruggeri |
51' | Berat Djimsiti | |||
60' | Rafael Tolói | |||
Viktor Gyökeres | 76' | |||
76' | Sead Kolasinac | |||
Pedro Gonçalves | 84' | |||
Daniel Bragança | 90+2' | |||
90+2' | Gianluca Scamacca |